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RION Launches Rion Vet to Transform Animal Health with First-in-Class Exosome Biologics; Appoints Industry Leader Mark Herthel as CEO; Announces Series A Fulfillment
RION, a clinical-stage regenerative medicine company and global leader in exosome-based therapeutics, today announced the formation of Rion Vet, a veterinary biotechnology company advancing platelet-derived exosome-based biologics to address major unmet needs in animal health. The company launches with exclusive global rights to RION’s proprietary Purified Exosome Product (PEP™) platform for veterinary use. Rion Vet anticipates bringing its first product, ePEP-01 for equine musculoskeletal disease, to market after this shelf-stable biologic has shown consistent results in clinical trials over nearly five years of research, discovery and development.
By RION · Via Business Wire · November 11, 2025
RION Engages Lonza to Scale Manufacturing Exosome Based Therapeutics
RION, a commercial and clinical-stage regenerative medicine company pioneering platelet-derived exosomes for both human and animal health applications, has announced a collaboration with Lonza, one of the world’s largest contract development and manufacturing organizations (CDMOs), to provide cGMP manufacturing and technical support for commercial scale production of its Purified Exosome Product™ (PEP™) drug substance for late phase clinical supply and beyond.
By RION · Via Business Wire · September 23, 2025
RION Launches INTENT Biologics to Develop Late-Stage Clinical Exosome-Based Therapies in Inflammation & Immunology; Appoints Biopharma Veteran Suneet Varma as CEO
RION, a clinical-stage regenerative medicine company and global leader in exosome-based therapeutics, today announced the formation of INTENT Biologics, a new independent biotechnology company focused exclusively on developing first-in-class exosome therapies for Inflammation & Immunology (I&I). INTENT Biologics launches with exclusive, perpetual worldwide rights to RION’s Purified Exosome Product (PEP™) biologic platform in I&I and will advance PEP Biologic™ into Phase 3 clinical development for advanced tissue regeneration and immune-mediated dermatologic indications.
By RION · Via Business Wire · September 9, 2025
RION names Biopharma Veteran Suneet Varma as Senior Advisor to Spearhead Expansion into Regenerative Therapeutics
RION, a clinical-stage regenerative medicine company at the forefront of exosome-based therapeutics, today announced the addition of Suneet Varma to their leadership team.
By RION · Via Business Wire · May 1, 2025
RION Announces First Patient Enrolled in Phase 1b Clinical Study Evaluating Purified Exosome Product™ (PEP™) for Knee Osteoarthritis
RION, a clinical-stage regenerative medicine company at the forefront of exosome-based therapeutics, today announced the enrollment of the first patient in its Phase 1b clinical study evaluating Purified Exosome Product™ (PEP™) for the treatment of Knee Osteoarthritis (OA). This milestone highlights RION’s commitment to advancing innovative regenerative therapies that address unmet medical needs.
By RION · Via Business Wire · March 11, 2025
RION Announces Final Patient Enrolled in the Phase 2 Clinical Study for Purified Exosome Product™ (PEP™) in Diabetic Foot Ulcers
RION, a clinical-stage regenerative medicine company at the forefront of exosome-based therapeutics, announced today that it has completed patient enrollment in its Phase 2 clinical trial for Purified Exosome Product™ (PEP™) in the treatment of Diabetic Foot Ulcers (DFUs). This milestone marks a significant step forward in the company’s mission to develop cutting-edge therapies addressing chronic wound care.
By RION · Via Business Wire · January 13, 2025
RION to Present at the 43rd Annual J.P. Morgan Healthcare Conference
RION, a clinical-stage regenerative medicine company revolutionizing healthcare through its exosome-based technology, announced today that its Co-Founder, Dr. Atta Behfar, will present at the 43rd Annual J.P. Morgan Healthcare Conference on Thursday, January 16, 2025, at 10:00 AM PST.
By RION · Via Business Wire · January 7, 2025
RION Expands Leadership Team with the Appointment of Five Renowned Experts to Advisory Boards
RION, a clinical-stage regenerative medicine company pioneering exosome-based therapeutics, today announced the appointment of five distinguished leaders to its Advisory Board. These new advisors bring decades of expertise in their respective fields, ranging from orthopedic & plastic surgery to infectious diseases, military medicine, biomanufacturing and government health strategy, further positioning RION as a leader in innovative regenerative medicine.
By RION · Via Business Wire · September 25, 2024
RION Announces Initiation of Phase 1b Clinical Study to Evaluate Purified Exosome Product™ (PEP™) for Knee Osteoarthritis
RION, at the forefront of exosome innovation and therapeutic application, has officially commenced a Phase 1b study aimed at assessing the efficacy and safety of Purified Exosome Product™ (PEP™), its exclusive exosome regenerative therapeutic, for the management knee osteoarthritis (Knee OA).
By RION · Via Business Wire · September 10, 2024
RION Announces First Patient Dosed in Phase 2 Clinical Study of Purified Exosome Product™ for Diabetic Foot Ulcers
RION, a clinical-stage regenerative medicine company at the forefront of exosome therapeutics, announced today the first subject was dosed in the Phase 2 clinical trial with its novel product, known as Purified Exosome Product™ (PEP™). This event marks a pivotal milestone in evaluating PEP™ as an innovative treatment for chronic conditions such as Diabetic Foot Ulcers (DFUs).
By RION · Via Business Wire · May 7, 2024
RION Expands Manufacturing Operations with Cutting-Edge Facility in Rochester, Minnesota
RION, a pioneer in regenerative medicine and exosome technology, has unveiled a major expansion of its manufacturing operations with the inauguration of a state-of-the-art facility in Rochester, Minnesota. In collaboration with Rochester Area Economic Development, Inc., this move represents a significant milestone in RION's mission to bolster its manufacturing capabilities in support of its groundbreaking Rion Aesthetics spin-off and its globally renowned skin and hair brand, (plated)™ Skin Science.
By RION · Via Business Wire · February 26, 2024
RION Announces Initiation of Phase 2A Clinical Study for Purified Exosome Product™ (PEP™) in Diabetic Foot Ulcers
RION, a clinical-stage regenerative medicine company, at the forefront of the exosome therapeutic revolution, has officially commenced a Phase 2A study aimed at assessing the efficacy and safety of its exclusive exosome regenerative therapeutic, known as Purified Exosome Product™ (PEP™), for the management of Diabetic Foot Ulcers (DFU).
By RION · Via Business Wire · January 30, 2024
Rion to Present at the 42nd Annual J.P. Morgan Healthcare Conference
Rion, a leader in regenerative medicine and exosome technology, today announced Dr. Atta Behfar, Co-Founder, will present at the 42nd Annual JP Morgan Healthcare Conference on Wednesday, January 10, 2024, at 02:00 PM. The presentation will showcase Rion's breakthrough developments in platelet-derived regenerative exosome technology and its significant impact across various regenerative medicine therapeutic areas.
By Rion · Via Business Wire · January 2, 2024
RION, Mayo Clinic, and the U.S. Army Medical Research Institute for Chemical Defense Receive $2.4M Department of Defense Award to Advance Exosome-Based Research in Pulmonary Therapeutics
RION, a leading clinical-stage regenerative medicine company, today announced that it will collaborate with Mayo Clinic and the U.S. Army Medical Research Institute for Chemical Defense (ICD) on a $2.4M grant awarded from the Department of Defense. This grant accelerates a critical research initiative aimed at exploring the therapeutic potential of RION's proprietary Purified Exosome Product™ (PEP™) for the treatment of Chronic Obstructive Pulmonary Disease (COPD) and other challenging pulmonary conditions, which can impact soldiers and veterans exposed to airborne hazards in war zones.
By RION · Via Business Wire · November 20, 2023
RION Announces the Advisory Appointments of John Ballantyne, Ph.D., to Chair of the Rion Scientific Advisory Board and Andrew D. Badley, M.D., to Chair of the Rion Medical Advisory Board
RION, a clinical-stage regenerative medicine company with breakthrough platform technology leveraging platelet-derived exosomes, announces the appointment of Dr. Ballantyne as Chair of the company’s Scientific Advisory Board and Dr. Andrew D. Badley as Chair of the Rion Medical Advisory Board. The company, founded by internationally recognized regenerative medicine experts Drs. Atta Behfar and Andre Terzic, continues to emerge in the regenerative therapeutics utilizing its proprietary manufacturing process and shelf-stable regenerative exosomes for flagship programs in wound healing, cardiology, and orthopedic indications.
By RION · Via Business Wire · January 25, 2023
RION Appoints Alisa Lask as Chief Commercial Officer
RION, a biotechnology company headquartered in Rochester, Minnesota pioneering new innovations in exosomes for therapeutic and aesthetic indications, today announced the appointment of Alisa Lask as Chief Commercial Officer.
By RION · Via Business Wire · January 14, 2022